N-Boc-O-Benzyl-D-serine budada saaraha CAS No.: 47173-80-8 98% nadiifinta min. Dhexdhexaadiyeyaasha
Qiyaasta Alaabta
| Magaca alaabta | N-Boc-O-Benzyl-D-serine |
| Magac kale | N-Boc-O-benzyl-D-serine; boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; Boc-(R) -2-amino-3-benzyloxypropionic acid; Boc-D-Ser(Bzl)-OH;Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
| CAS Maya. | 47173-80-8 |
| qaacidada molecular | C15H21NO5 |
| Miisaanka molecular | 295.33 |
| daahirnimo | 98% |
| Baakad | 1kg/bac;25kg/durbaan |
| Codsiga | Dhexdhexaadiye |
hordhaca alaabta
N-Boc-O-Benzyl-D-serine waa isku-darka kasbaday fiiro gaar ah dhanka kimistariga organic iyo cilmi-baarista dawooyinka. Xaruntan, oo sidoo kale loo yaqaan Boc-D-serine, waa ka soo jeeda amino acid D-serine waxaana si weyn loogu isticmaalaa isku dhafka daawooyinka kala duwan iyo molecules bioactive. N-Boc-O-Benzyl-D-serine waa budo crystalline cad ama ka baxsan taas oo si yar ugu milmay biyaha kuna milmay dareerayaasha organic sida methanol iyo ethanol. Waa nooc ka mid ah D-serine, oo ah amino acid-ka aan-proteinogenic-ka ahayn oo door muhiim ah ka ciyaara habka dhexe ee neerfayaasha sida co-agonist ee N-methyl-D-aspartate (NMDA). N-Boc (tert-butoxycarbonyl) iyo kooxaha O-Benzyl ee xaruntu waxay u adeegaan sidii kooxo ilaalin ah, oo u oggolaanaya khalkhalgelinta xulashada amino acid inta lagu jiro kiimikada kiimikada.N-Boc-O-Benzyl-D-serine waxaa ugu horreyn loo isticmaalaa sida dhismaha dhismaha ee isku-dhafka peptides iyo peptidomimetics. Peptides waa silsilado gaagaaban oo amino acids ah kuwaas oo doorar kala duwan ka ciyaara hababka bayoolojiga waxayna aad u daneeyaan helitaanka iyo horumarinta daroogada. Iyadoo lagu darayo N-Boc-O-Benzyl-D-serine ee isku xigxiga peptide, farmashiyeyaashu waxay bedeli karaan sifooyinka iyo hawlaha peptides ka soo baxa, taas oo ka dhigaysa qalab qiimo leh oo naqshadeynta wakiilada dawooyinka cusub. Intaa waxaa dheer, N-Boc-O-Benzyl-D-serine waxaa lagu shaqaaleysiiyay diyaarinta dhexdhexaadiyeyaasha dawooyinka iyo maaddooyinka dawooyinka firfircoon (APIs). Falcelinteeda kala duwan iyo la jaanqaadka falcelinta kiimikaad ee kala duwan ayaa ka dhigaysa qayb la raadinayo oo ka mid ah isku-darka unugyo dabiici ah oo kakan oo leh awood daweyn.
Muuqaal
(1) Nadiifin sare: N-Boc-O-Benzyl-D-serine waxay ku heli kartaa alaab saafi ah iyada oo loo marayo sifaynta hababka wax soo saarka. Nadiifin sare waxay ka dhigan tahay helitaan noole oo wanaagsan iyo falcelin xun oo yar.
(2) Badbaadada: Badbaadada sare, falcelin xun oo yar.
(3) Xasilloonida: N-Boc-O-Benzyl-D-serine waxay leedahay xasillooni wanaagsan waxayna sii wadi kartaa dhaqdhaqaaqeeda iyo saameynteeda hoos yimaada deegaan kala duwan iyo xaaladaha kaydinta.
Codsiyada
Ku daridda N-Boc-O-Benzyl-D-serine ee molecules-ka daroogada ayaa la muujiyey inay bixiso guryaha farmashiyaha iyo farmashiyaha la jecel yahay. Peptidomimetics oo laga soo qaatay N-Boc-O-Benzyl-D-serine waxay muujisay xasillooni la xoojiyey, bioavailability, iyo bartilmaameed gaar ah, taas oo ka dhigaysa musharaxiin rajo leh daaweynta cudurrada kala duwan, oo ay ku jiraan kansarka, cudurrada faafa, iyo cilladaha neerfaha. Intaa waxaa dheer, awoodda si wax looga beddelo N-Boc-O-Benzyl-D-serine moiety waxay u oggolaanaysaa hagaajinta musharraxiinta daroogada, iyada oo la wanaajinayo waxtarkooda iyo astaamaha badbaadada.
