Soo saaraha budada Beta-Nicotinamide Adenine Dinucleotide (NAD+) Lambarka CAS: 53-84-9 98.5% daahirnimo ugu yaraan maaddooyinka dheeraadka ah
Cabbiraadaha Badeecada
| Magaca alaabta | Nikotinamide Mononucleotide |
| Magac kale | NICOTINAMIDE RIBOTIDE; BETA-Nicotinamide Mononucleotide NikotinaMide Ribonucleotide; β-Nicotinamide Mononucleotide () |
| Lambarka CAS. | 1094-61-7 |
| Qaacidada moolikaalka | C11H15N2O8P |
| Miisaanka molecular-ka | 334.22 |
| Daahirnimo | 98.0% |
| Muuqaalka | Budada cad |
| Baakad | 1kg/bac 10kg/durbaan |
| Codsiga | Ka-hortagga Gabowga |
Soo bandhigida badeecada
Beta-Nicotinamide Adenine Dinucleotide (Beta-NAD+), oo loo yaqaan Beta-NAD, waa molecule muhiim ah oo laga helo dhammaan unugyada nool. Waxay door muhiim ah ka ciyaartaa hababka kala duwan ee bayoolojiga, oo ay ku jiraan dheef-shiid kiimikaadka tamarta iyo calaamadaynta unugyada. Beta-Nicotinamide Adenine Dinucleotide waxaa laga sameeyaa niacin (vitamin B3) iyo ATP (adenosine triphosphate) iyada oo loo marayo taxane fal-celin enzymatic ah. Inta lagu jiro neefsashada unugyada, Beta-Nicotinamide Adenine Dinucleotide waa coenzyme kaas oo fududeeya wareejinta elektarooniga inta lagu jiro burburka gulukooska iyo biomolecules kale. Wareejinta elektaroonigan waxay muhiim u tahay soo saarista ATP, lacagta tamarta guud ee unugga. Iyada oo aan lahayn Beta-Nicotinamide Adenine Dinucleotide, unugyadu si wax ku ool ah uma soo saari karaan tamar oo ma qaban karaan shaqooyinkooda muhiimka ah. Marka laga soo tago doorkeeda dheef-shiid kiimikaadka tamarta, Beta-Nicotinamide Adenine Dinucleotide waxay u adeegtaa sidii substrate enzymes kala duwan oo ku lug leh calaamadaynta unugyada iyo nidaaminta. Koox ensaymyo ah oo si fiican loo yaqaan oo isticmaala Beta-Nicotinamide Adenine Dinucleotide waa Sirtuins, kuwaas oo ku lug leh habab kala duwan oo unugyo ah, oo ay ku jiraan hagaajinta DNA-da, muujinta hidda-wadaha, iyo gabowga. Ensaymyadani waxay u baahan yihiin Beta-Nicotinamide Adenine Dinucleotide oo ah cofactor si ay u sameeyaan firfircoonidooda ensaymikada.
Muuqaalka
(1) Nadiifnimo sare: NAD+ waxay heli kartaa badeecooyin saafi ah oo heer sare ah iyada oo loo marayo hababka wax soo saarka ee sifeynta. Nadiifnimo sare waxay ka dhigan tahay helitaan wanaagsan oo noolaha ah iyo falcelin xun oo yar.
(2) Badbaadada: Badbaado sare, falcelin xun oo yar.
(3) Xasillooni: NAD+ waxay leedahay xasillooni wanaagsan waxayna ilaalin kartaa dhaqdhaqaaqeeda iyo saameynteeda iyadoo la raacayo jawiyo iyo xaalado kaydin oo kala duwan.
Codsiyada
NAD+ waa coenzyme oo door muhiim ah ka ciyaara noocyo kala duwan oo hababka bayoolojiga ah, oo ay ku jiraan dheef-shiid kiimikaadka tamarta, dayactirka DNA-da, iyo calaamadaynta unugyada. NAD+ sidoo kale waxay ku lug leedahay hababka kale ee unugyada sida dayactirka DNA-da, muujinta hidda-wadaha, iyo calaamadaynta kaalshiyamka. Waa muhiim in la ilaaliyo gabowga caafimaadka qaba, maadaama heerarka NAD+ ay hoos u dhacaan da'da, taasoo horseedaysa hoos u dhaca dheef-shiid kiimikaadka unugyada iyo dhaawaca unugyada oo kordha. Heerarka NAD+ waxay hoos u dhacaan da'da, hoos u dhacanina wuxuu la xiriiraa cudurrada la xiriira da'da. Kaabista horudhaca NAD+ waxaa la muujiyay inay kordhiso heerarka NAD+ waxayna leedahay saameyn gabowga caafimaad leh oo suurtagal ah.
