Soo saaraha budada nicotinamide riboside ee la dhimay Lambarka CAS:19132-12-8 98% daahirnimo ugu yaraan maaddooyinka dheeraadka ah
Cabbiraadaha Badeecada
| Magaca alaabta | Riboside nicotinamide oo la dhimay (NRH) |
| Magac kale | 1-(beta-D-Ribofuranosyl)-1,4-dihydronicotinamide；1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4H-pyridine-3-carboxamide； 1,4-dihydro-1beta-d-ribofuranosyl-3-pyridinecarboxamide； 1-(beta-D-ribofuranosyl)-1,4-dihydropyridine-3-carboxamide; |
| Lambarka CAS. | 19132-12-8 |
| Qaacidada moolikaalka | C11H16N2O5 |
| Miisaanka molecular-ka | 256.26 |
| Daahirnimo | 98% |
| Baakad | 1kg/bac;25kg/durbaan |
| Codsiga | alaabta ceeriin ee kabka cuntada |
Soo bandhigida badeecada
Nicotinamide riboside (NRH) oo la dhimay waa nooc cusub oo nicotinamide riboside ah waana horudhac xooggan oo NAD+ ah, oo ah coenzyme ku lug leh habab kala duwan oo unugyo ah, oo ay ku jiraan dheef-shiid kiimikaadka tamarta iyo dayactirka DNA-da. Marka aan gabowno, heerarka NAD+ ee jirka ayaa hoos u dhaca, taas oo la xiriirta dhibaatooyin caafimaad oo kala duwan oo la xiriira da'da. Iyadoo la kordhinayo heerarka NAD+, NRH waxay gacan ka geysan kartaa hagaajinta shaqada mitochondrial, taas oo muhiim u ah wax soo saarka tamarta unugyada. Tani, markeeda, waxay horseedi kartaa koror ku yimaada heerarka tamarta iyo firfircoonida guud. Intaa waxaa dheer, NRH waxay gacan ka geysan kartaa taageeridda heerarka kolestaroolka caafimaadka qaba iyo hagaajinta shaqada wadnaha iyo xididdada dhiigga. Cilmi-baaristu waxay muujinaysaa in NRH ay taageeri karto caafimaadka maskaxda iyo shaqada garashada, taasoo laga yaabo inay ka hortagto hoos u dhaca garashada ee la xiriira da'da. Iyadoo kor u qaadaysa gabowga maskaxda caafimaadka qaba iyo taageeridda shaqada neerfaha, NR waxay saameyn ku yeelan kartaa ilaalinta firfircoonida garashada marka aan gabowno.
Muuqaalka
(1) Nadiifnimo sare: Riboside nicotinamide oo la dhimay waxay heli kartaa badeecooyin saafi ah iyada oo loo marayo sifeynta hababka wax soo saarka. Nadiifnimo sare waxay ka dhigan tahay helitaan wanaagsan oo noolaha ah iyo falcelin xun oo yar.
(2) Badbaadada: Badbaado sare, falcelin xun oo yar.
(3) Xasilloonida: Riboside-ka nicotinamide ee la dhimay wuxuu leeyahay xasillooni wanaagsan wuxuuna ilaalin karaa firfircoonidiisa iyo saameyntiisa jawiyo iyo xaalado kaydin oo kala duwan.
Codsiyada
Riboside nicotinamide oo la dhimay ayaa loo isticmaali karaa kaabis ahaan dhinaca ka hortagga gabowga. Marka laga soo tago awooddeeda ka hortagga gabowga, NRH waxaa lagu darsay doorka ay ka qaadato hagaajinta caafimaadka dheef-shiid kiimikaadka. Guud ahaan, riboside nicotinamide oo la dhimay wuxuu leeyahay codsiyo kala duwan, oo u dhexeeya caafimaadka ka hortagga gabowga iyo dheef-shiid kiimikaadka. Maadaama cilmi-baarista aaggan ay sii socoto, NRH waxay noqon kartaa mid qiimo leh oo lagu daro si kor loogu qaado caafimaadka guud iyo fayoobaanta.
