Soo saaraha budada N-Boc-O-Benzyl-D-serine Lambarka CAS:47173-80-8 98% daahirnimo ugu yaraan dhexdhexaad ah
Cabbiraadaha Badeecada
| Magaca alaabta | N-Boc-O-Benzyl-D-serine |
| Magac kale | N-Boc-O-benzyl-D-serine; Boc-O-benzyl-D-serine; O-Benzyl-N-(tert-butoxycarbonyl)-D-serine; Boc-(R)-2-amino-3-benzyloxypropionic asiidh; Boc-D-Ser(Bzl)-OH; Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
| Lambarka CAS. | 47173-80-8 |
| Qaacidada moolikaalka | C15H21NO5 |
| Miisaanka molecular-ka | 295.33 |
| Daahirnimo | 98% |
| Baakad | 1kg/bac;25kg/durbaan |
| Codsiga | Dhexdhexaadin |
Soo bandhigida badeecada
N-Boc-O-Benzyl-D-serine waa isku-dhis kasbaday dareen weyn oo ku saabsan cilmiga kiimikada dabiiciga ah iyo cilmi-baarista dawooyinka. Isku-darkaan, oo sidoo kale loo yaqaan Boc-D-serine, waa nooc ka mid ah amino acid D-serine waxaana si weyn loogu isticmaalaa isku-darka daawooyinka kala duwan iyo molecules-ka noolaha firfircoon. N-Boc-O-Benzyl-D-serine waa budo crystalline ah oo cad ilaa caddaan ah oo si yar ugu milma biyaha oo ku milma dareerayaasha dabiiciga ah sida methanol iyo ethanol. Waa nooc ka mid ah D-serine, kaas oo ah amino acid aan borotiin ahayn oo door muhiim ah ka ciyaara nidaamka neerfaha dhexe isagoo ah mid ka mid ah soo-dhoweeyaha N-methyl-D-aspartate (NMDA). Kooxaha N-Boc (tert-butoxycarbonyl) iyo O-Benzyl ee ku jira isku-dhafka waxay u adeegaan kooxo ilaalin ah, taasoo u oggolaanaysa in la isticmaalo amino acid-ka xulashada ah inta lagu jiro isku-darka kiimikada. N-Boc-O-Benzyl-D-serine waxaa ugu horreyn loo isticmaalaa sidii baloog dhisme oo lagu sameeyo peptides-ka iyo peptidomimetics-ka. Peptides-ku waa silsilado gaagaaban oo amino acids ah oo doorar kala duwan ka ciyaara hababka bayoolojiga waxayna aad u xiiseeyaan helitaanka iyo horumarinta daawada. Iyagoo ku daraya N-Boc-O-Benzyl-D-serine taxanaha peptide-ka, kiimikooyinku waxay beddeli karaan sifooyinka iyo hawlaha peptide-yada ka dhasha, taasoo ka dhigaysa qalab qiimo leh oo ku saabsan naqshadeynta wakiilada dawooyinka cusub. Intaa waxaa dheer, N-Boc-O-Benzyl-D-serine waxaa loo isticmaalaa diyaarinta daawooyinka dhexdhexaadka ah iyo maaddooyinka dawooyinka firfircoon (APIs). Falcelinta kala duwan iyo iswaafajinta falcelinta kiimikada ee kala duwan waxay ka dhigaysaa qayb la raadsado oo ku jirta isku-darka molecules-ka dabiiciga ah ee adag oo leh awood daaweyn.
Muuqaalka
(1) Nadiifnimo sare: N-Boc-O-Benzyl-D-serine waxay heli kartaa badeecooyin saafi ah oo sarreeya iyada oo loo marayo hababka wax soo saarka ee sifeynta. Nadiifnimo sare waxay ka dhigan tahay helitaan wanaagsan oo noolaha ah iyo falcelin xun oo yar.
(2) Badbaadada: Badbaado sare, falcelin xun oo yar.
(3) Xasillooni: N-Boc-O-Benzyl-D-serine waxay leedahay xasillooni wanaagsan waxayna ilaalin kartaa firfircoonideeda iyo saameynteeda iyadoo la raacayo jawiyo iyo xaalado kaydin oo kala duwan.
Codsiyada
Ku darista N-Boc-O-Benzyl-D-serine molecules-ka daawada ayaa la muujiyay inay bixiso sifooyin farmashiye iyo farmashiye-dareen oo la rabo. Peptidomimetics-ka laga soo qaatay N-Boc-O-Benzyl-D-serine waxay muujiyeen xasillooni la xoojiyay, helitaan bioavailability, iyo gaar ahaansho bartilmaameed, taasoo ka dhigaysa musharrixiin rajo leh oo loogu talagalay daaweynta cuduro kala duwan, oo ay ku jiraan kansarka, cudurrada faafa, iyo xanuunnada neerfaha. Intaa waxaa dheer, awoodda lagu beddeli karo qaybta N-Boc-O-Benzyl-D-serine waxay u oggolaanaysaa hagaajinta musharrixiinta daroogada, iyadoo la wanaajinayo waxtarkooda iyo astaamaha badbaadada.
