1,4-DihydronicotinaMide Riboside saaraha budada CAS No.: 19132-12-8 98% nadiifinta min.maaddooyinka dheeriga ah
Qiyaasta Alaabta
| Magaca alaabta | 1,4-DihydronicotinaMide Riboside |
| Magac kale | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| CAS Maya. | 19132-12-8 |
| qaacidada molecular | C11H16N2O5 |
| Miisaanka molecular | 256.26 |
| daahirnimo | 98% |
| Muuqashada | budo cad |
| Baakad | 1kg/bac;25kg/durbaan |
| Codsiga | Kaabista cuntada alaabta ceeriin |
hordhaca alaabta
1,4-dihydronicotinamide riboside, oo sidoo kale loo yaqaan NRH.Qaabka la dhimay ee NRH waa horudhac awood leh oo NAD + ka caawiya inuu buuxiyo heerarkiisa unugga.
Marka hore, waxaa muhiim ah in la fahmo doorka NAD + ee jirka.NAD + waa coenzyme ku lug leh habab badan oo gacanta ah, oo ay ku jiraan dheef-shiid kiimikaad tamarta, hagaajinta DNA, iyo muujinta hidda-wadaha.Markaan da'eyno, heerarkayaga NAD + ayaa hoos u dhacay, kaas oo lagu lug yeeshay habka gabowga iyo cudurrada da'da la xiriira.Tani waxay keentay xiisaha sii kordhaya ee aqoonsiga molecules kuwaas oo kor u qaadi kara heerarka NAD + ee jirka, iyo 1,4-dihydronicotinamide riboside waa mid ka mid ah unugyadaas.
1,4-dihydronicotinamide riboside waa horudhac awood leh oo NAD + ah, cilmi baaris ayaa muujisay in ay si wax ku ool ah kor ugu qaadi karto heerarka NAD + unugyada.Tani waxay keentay in la qiyaaso in 1,4-dihydronicotinamide riboside supplementation ay yeelan karto awood daweyn oo xaalado caafimaad oo kala duwan, oo ay ku jiraan cilladaha dheef-shiid kiimikaadka, cudurrada neurodegenerative, iyo hoos u dhaca gabowga.
Dhab ahaantii, waxaa jira caddaymo muujinaya in 1,4-dihydronicotinamide riboside laga yaabo inay xitaa ka waxtar badan tahay molecule waalidkeed, nicotinamide riboside, ee kordhinta heerarka NAD +.Tani waa sababta oo ah 1,4-dihydronicotinamide riboside waa wax-yareeya awood badan, taasoo la micno ah inay ku fiican tahay ku-deeqidda elektarooniga jidka isku-dhafka NAD +.Natiijo ahaan, waxay awood u leedahay inay si hufan u shido wax soo saarka gacanta ee NAD +.
Marka lagu daro doorkeeda NAD + biosynthesis, 1,4-dihydronicotinamide riboside sidoo kale waxay leedahay sifooyinka antioxidant.Cadaadiska Oxidative, kaas oo ka dhasha isku dheelitir la'aanta u dhaxaysa xagjirka xorta ah iyo antioxidants ee jirka, ayaa ku lug leh cuduro badan, oo ay ku jiraan kansarka, cudurrada wadnaha iyo xididada, iyo xanuunada neurodegenerative.Iyadoo la xoqayo xagjirnimada xorta ah iyo yaraynta waxyeelada oksaydhka, 1,4-dihydronicotinamide riboside waxay bixin kartaa faa'iidooyin caafimaad oo dheeraad ah oo ka baxsan doorkeeda NAD + horudhac.
Muuqaal
(1) Nadiifin sare: 1,4-dihydronicotinamide riboside waxay ku heli kartaa alaab saafi ah iyada oo loo marayo hababka wax soo saarka ee la safeeyey.Nadaafadda sare waxay ka dhigan tahay helitaan noole oo wanaagsan iyo falcelin xun oo yar.
(2) Badbaadada: 1,4-dihydronicotinamide riboside waa badeeco dabiici ah oo la xaqiijiyay inay badbaado u tahay jidhka bini'aadamka.Inta lagu jiro qiyaasta qiyaasta, ma jiraan waxyeelo sun ah.
(3) Xasilloonida: 1,4-dihydronicotinamide riboside waxay leedahay xasillooni wanaagsan waxayna sii wadi kartaa dhaqdhaqaaqeeda iyo saameynteeda meelo kala duwan iyo xaaladaha kaydinta.
Codsiyada
1,4-Dihydronicotinamide waa qaabka la dhimay ee riboside nicotinamide.Waxay ku jiri kartaa labadaba foomamka oksaydhka ah iyo kuwa la dhimayba waxayna horudhac u tahay NAD-da cusub ee la helay (nicotinamide adenine dinucleotide), oo loo heli karo kabitaan ahaan, iyadoo NRH ay tahay mid ka awood badan oo ka dhaqso badan NAD + horudhaca NR.
