Soo saaraha budada 7P Compound CAS No.: 1890208-58-8 99% nadiifinta min.maaddooyinka dheeriga ah
Qiyaasta Alaabta
| Magaca alaabta | Isku dhafka 7P |
| Magac kale | Isku dhafka7P;2-[(2-methoxyphenyl) [(4-methylphenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide; 2- (N- (2-methoxyphenyl) -4-methylphenylsulfonamido) - (4-methoxypyridin-3-yl) acetamide |
| CAS Maya. | 1890208-58-8 |
| qaacidada molecular | C22H23N3O5S |
| Miisaanka molecular | 441.51 |
| daahirnimo | 99.0% |
| Muuqashada | budo cad |
| Codsiga | Nootropic |
hordhaca alaabta
Isku-dhafka 7p ayaa la muujiyay si uu u kiciyo kobaca GAP-43-positive axon ee qaabka xayawaanka ee dhaawaca dareemayaasha indhaha, taas oo soo jeedinaysa in waxqabadka neurite ee ka soo baxa xarunta 7p in vitro uu u tarjumayo kicinta dib u soo kabashada axon ee vivo.Isku-dhafka 7P budada waa caddaan ama budo cad-cad oo loo soo saaray sidii isku-darka tandem si loo aqoonsado laba-qabta tromboxane antagonist antagonist.Runtii, xarunta 7p waxay muujinaysaa xulashada prostaglandin I2 synthase (PTGIS, CYP8A1) ee ka sarreeya thromboxane synthase (CYP5A1).Nootropic waa walax kasta oo gacan ka geysata hagaajinta shaqada maskaxda, oo ay ku jiraan xusuusta, feejignaanta, niyadda, iyo xitaa garaadka.Waxay u dhaxayn karaan kooxo cuntooyin gaar ah ama walxo ilaa xeryo ay dadku sameeyeen oo si gaar ah loogu talagalay inay caawiyaan shaqada maskaxda iyo faa'iidooyinka kale.Qalabka Nootropic 7P budada waxay kor u qaadaa ka soo baxa Gap-43 axon togan, taas oo kicinaysa dib u soo kabashada axonal ee vivo.Xarunta tayada sare leh ee 7p waxaa loogu talagalay in lagu hagaajiyo isuduwidda, wanaajiso niyadda iyo caawinta la dagaalanka daalka.Waxa kale oo ay ka hortagtaa oksaydheynta maskaxda waxayna ka caawisaa la dagaalanka dhaawaca maskaxda ee ay keento isticmaalka khamriga.
Codsiyada
Neurons ee habka dhexe ee neerfayaasha (CNS) waxay ku guuldareystaan inay dib u soo nooleeyaan axon ka dib dhaawaca, taas oo qayb ahaan sharxaysa soo kabashada shaqeynta liidata ee bukaanada qaba dhaawacyada iyo cudurrada neurodegenerative.Compound 7p, kaas oo kor u qaadaya koritaanka neurite ee neerfayaasha asaasiga ah ee dhaqameed ee ka soo jeeda hippocampus, kiliyaha maskaxda, iyo retina, oo keena dib u soo kabashada dareemayaasha indhaha ee qaabka xayawaanka ee dhaawaca dareemayaasha indhaha.Waxay kaloo kordhisaa isuduwidda, waxay daweysaa dhaawaca maskaxda ee la xiriira khamriga, waxayna ka hortagtaa oksaydhka agagaarka maskaxda.Waxa kale oo ay caawisaa in la hagaajiyo niyadda qofka iyo la dagaalanka daalka.Intaa waxaa dheer 7P waxay muujisay dhaqdhaqaaqa ugu sarreeya ee ka soo horjeeda burooyinka ilmo-galeenka iyada oo hagaajinaysa qaab-dhismeedka yar-yar ee qaab-ku-tiirsanaan.Hagaajinta dheeraadka ah ee isku dhafka 7p iyo qeexida habka ay u kiciso dib u soo kabashada axon ee vivo waxay siin doontaa fikradda dadaalka mustaqbalka ee lagu xoojinayo xeeladaha daaweynta.
