9-Methyl-9H-beta-carboline Lambarka CAS:2521-07-5 99% daahirnimo ugu yaraan. loogu talagalay kabka Waxyaabaha ku jira
Cabbiraadaha Badeecada
| Magaca alaabta | 9-Me-BC |
| Magac kale | 9-Methyl-9H-beta-karboline9-methyl-9h-pyrido[3,4-b]indole 9H-Pyrido[3,4-b]indole, 9-methyl- 9-Methyl-9H-pyrido(3,4-b)indole 9-methylpyrido[3,4-b]indole 9-methyl-beta-karboline 9-methylnorharman 9-methyl-9h-beta-karboline 9H-Pyrido(3,4-b)indole, 9-methyl- 9-Methylnorharmane |
| Lambarka CAS. | 2521-07-5 |
| Qaacidada moolikaalka | C12H10N2 |
| Miisaanka molecular-ka | 182.22 |
| Daahirnimo | 99% |
| Muuqaalka | Adag oo jaalle ah |
| Baakad | 1kg/Bac; 25kg/Dubaan Kaarboor ah |
| Codsiga | Waxyaabaha Kaabista Cuntada ah |
Soo bandhigida badeecada
9-Methyl-β-carboline (9-Me-BC) waa amiin heterocyclic ah oo ka tirsan qoyska β-carboline waana kiimiko cilmi baaris ah oo macmal ah. Waa methylated derivative oo ka timid β-carboline. Qaab-dhismeedka kiimikada ee 9-Me-BC wuxuu ka kooban yahay xudunta β-carboline iyo koox methyl ah oo ku xiran booska 9-aad ee nidaamka pyridinium[3,4-b]indole giraanta. 9-Me-BC uma muuqato inay leedahay ilo dabiici ah oo la yaqaan. 9-Me-BC waxay kor u qaaddaa garashada iyada oo loo marayo farsamooyin badan. Waxay kor u qaaddaa tyrosine hydroxylase, enzyme-ka xaddidaya heerka ee isku-darka dopamine, taasoo horseedaysa heerarka dopamine oo kordha. 9-Me-BC sidoo kale waxay joojisaa dhaqdhaqaaqa monoamine oxidase (MAO), taasoo ka hortagaysa burburka dopamine iyo neurotransmitters-ka kale ee monoamine. Intaa waxaa dheer, 9-Me-BC waxay kicisaa astrocytes-ka si ay u muujiyaan arrimaha neerfaha, iyagoo kor u qaadaya koritaanka neerfaha iyo badbaadada. Dadka caafimaadka qaba, 9-Me-BC waxay horumarin kartaa garashada iyadoo hagaajinaysa heerarka neerfaha iyo taageeridda koritaanka neerfaha. Tani waxay hagaajin kartaa xusuusta, feejignaanta, iyo barashada. Awoodda isku-dhafka ah ee lagu kordhinayo heerarka BDNF iyo NGF ayaa sidoo kale ka caawin karta caafimaadka garashada muddada dheer, taasoo ka dhigaysa 9-Me-BC doorasho caan ah oo loogu talagalay kuwa doonaya inay horumariyaan waxqabadka maskaxda iyo ka hortagga hoos u dhaca garashada.
Muuqaalka
(1) Nadiifnimo sare: 9-Methyl-9H-beta-carboline waxay heli kartaa badeecooyin saafi ah iyada oo loo marayo hababka wax soo saarka ee la safeeyey. Nadiifnimo sare macnaheedu waa helitaan wanaagsan oo noolaha ah.
(2) Xasillooni: 9-Methyl-9H-beta-carboline waxay leedahay xasillooni wanaagsan waxayna ilaalin kartaa firfircoonideeda iyo saameynteeda iyadoo la raacayo jawiyo iyo xaalado kaydin oo kala duwan.
(3) Rajooyinka horumarinta: Iyada oo ay ugu wacan tahay sifooyinka kala duwan ee 9-Methyl-9H-beta-carboline, horumarinteedu waxay heshay fiiro gaar ah waxayna leedahay cilmi-baaris ballaaran iyo rajooyin ku saabsan adeegsiga.
Codsiyada
9-Me-BC waxaa ugu horreyn loo isticmaalaa kor u qaadida garashada iyo difaaca neerfaha. Waxaa loo raadsadaa awooddeeda ay ku horumarin karto xusuusta, waxbarashada, iyo waxqabadka guud ee maskaxda. Intaa waxaa dheer, sifooyinka difaaca neerfaha ee 9-Me-BC waxay u oggolaanayaan inay ka ilaaliso neerfayaasha dhaawaca oo ay taageerto caafimaadka maskaxda. 9-Methyl-β-carboline waxaa si weyn loogu isticmaalaa warshadaha dawooyinka, sunta cayayaanka, iyo rinjiga iyadoo ah walxo ceeriin ah iyo dhexdhexaad. Intaa waxaa dheer, waxaa sidoo kale loo isticmaali karaa in lagu sameeyo isku-darka walxaha firfircoon ee bayoolojiga, sida kuwa leh saamaynta bakteeriyada iyo ka-hortagga bararka.
