Soo saaraha budada Nefiracetam CAS No.: 77191-36-7 99% nadiifinta min. maaddooyinka dheeriga ah
Fiidiyowga Alaabta
Qiyaasta Alaabta
Magaca alaabta | Nefiracetam |
Magac kale | n- (2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamide; NEFIRACETAM; 2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide; dm9384; n- (2,6-dimethylphenyl) -2-oxo-1-pyrrolidineacetamid; DM-9384, (2- (2-Oxopyrrolidin-1-yl) -N- (2,6-dimethylphenyl) -acetamide; DMPA |
CAS Maya. | 77191-36-7 |
qaacidada molecular | C14H18N2O2 |
Miisaanka molecular | 246.3 |
daahirnimo | 99.0% |
Muuqashada | Budada cad |
Baakad | 25 kg / foosto |
Codsiga | nootropic |
hordhaca alaabta
Nefiracetam waxaa iska leh qoyska piracetam, oo ah nooc ka mid ah dawooyinka loo yaqaano sifooyinka garaadka-kor u qaada. Nefiracetam waxaa markii ugu horreysay la sameeyay horraantii 1980-meeyadii waxayna si dhakhso ah u soo jiidatay dareenka sababtoo ah habka gaarka ah ee ficilka iyo codsiyada daweynta ee suurtagalka ah. Xaruntan jinsiyadeed waxaa loo maleynayaa in ay saameynayso neurotransmitters iyo reseptors ee maskaxda, ugu dambeyntii kor u qaadida awoodaha garashada oo la hagaajiyay. Nefiracetam wuxuu ugu horreyn saameeyaa heerarka maskaxda ee acetylcholine, neurotransmitter muhiim ah oo mas'uul ka ah xusuusta, barashada, iyo shaqada garashada. Iyada oo la beddelayo reseptors acetylcholine, nefiracetam waxay kor u qaadaysaa xidhiidhka kordhay ee u dhexeeya neerfayaasha, taas oo kor u qaadeysa balaastikada synaptik iyo hagaajinta xajinta xusuusta. Intaa waxaa dheer, nefiracetam waxay la falgalaan gamma-aminobutyric acid (GABA) reseptors si ay u caawiyaan dheelitirka milieu neurotransmitter. Iyada oo si togan u saameynaysa neurotransmitters excitatory iyo xannibaadyada, nefiracetam waxay ka caawisaa ilaalinta shaqada maskaxda ee ugu fiican, taas oo hagaajinaysa diiradda, dareenka, iyo guud ahaan waxqabadka garashada.
Muuqaal
(1) Nadiifin sare: Nefiracetam waxay ku heli kartaa alaab saafi ah iyada oo loo marayo sifaynta hababka wax soo saarka. Nadiifin sare waxay ka dhigan tahay helitaan noole oo wanaagsan iyo falcelin xun oo yar.
(2) Badbaadada: Badbaadada sare, falcelin xun oo yar.
(3) Xasilooni: Nefiracetam waxay leedahay xasillooni wanaagsan waxayna sii wadi kartaa dhaqdhaqaaqeeda iyo saameynteeda meelo kala duwan iyo xaaladaha kaydinta.
Codsiyada
Nefiracetam waa derivative hydrophobic of piracetam, taas oo guud ahaan loo arkaa in ay tahay walax ka mas'uul ah daahfurka ee channels calcium ee jirka iyo kala iibsiga aan tooska ahayn ee walxaha calaamadaha excitatory sida agonist qayb ka mid ah kanaalka calcium ion. Goobta isku-xidhka Glycine ee soo-dhoweeyaha NDMA. Iyada oo loo marayo saamaynta ay ku leedahay kiliyaha maskaxda, nefiracetam waxay kor u qaadi kartaa awoodaha garashada iyo ka hortagga waxbarashada iyo xusuusta daciifka ah. Ma laha muscarinic reseptor agonist ama guryaha ka soo horjeeda, mana joojinayso dhaqdhaqaaqa acetylcholinease. Sidaa darteed, saameynteeda anti-amnestic iyo xoojinta xusuusta ayaa lagu gaaraa iyada oo la hagaajinayo sii-deynta acetylcholine ee kiliyaha maskaxda.