Soo saaraha budada Nefiracetam Lambarka CAS: 77191-36-7 99% daahirnimo ugu yaraan maaddooyinka dheeraadka ah
Fiidiyowga Badeecada
Cabbiraadaha Badeecada
| Magaca alaabta | Nefiracetam |
| Magac kale | n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM; 2-oxo-1-pyrrolidinylaseticacid, 2,6-dimethylanilide; dm9384; n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid; DM-9384,(2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide); DMMPA |
| Lambarka CAS. | 77191-36-7 |
| Qaacidada moolikaalka | C14H18N2O2 |
| Miisaanka molecular-ka | 246.3 |
| Daahirnimo | 99.0% |
| Muuqaalka | Budada cad |
| Baakad | 25 kg/foosto |
| Codsiga | nootropic |
Soo bandhigida badeecada
Nefiracetam waxay ka tirsan tahay qoyska piracetam, oo ah nooc daawooyin ah oo loo yaqaan sifooyinkooda kor u qaadista garashada. Nefiracetam waxaa markii ugu horreysay la sameeyay horraantii 1980-meeyadii waxayna si dhakhso ah u soo jiidatay dareenka sababtoo ah farsamo gaar ah oo ficil ah iyo codsiyada daaweynta ee suurtagalka ah. Isku-darkaan jinsiga ah waxaa loo maleynayaa inuu saameeyo neerfayaasha iyo soo-dhoweeyayaasha maskaxda, ugu dambeyntiina wuxuu kor u qaadaa awoodaha garashada ee la hagaajiyay. Nefiracetam wuxuu si weyn u saameeyaa heerarka maskaxda ee acetylcholine, oo ah neerfayaasha muhiimka ah ee mas'uulka ka ah xusuusta, waxbarashada, iyo shaqada garashada. Iyadoo la beddelayo soo-dhoweeyayaasha acetylcholine, nefiracetam wuxuu kor u qaadaa isgaarsiinta sii kordheysa ee u dhaxaysa neerfayaasha, taasoo kor u qaadaysa dabacsanaanta synaptic iyo hagaajinta haynta xusuusta. Intaa waxaa dheer, nefiracetam waxay la falgashaa soo-dhoweeyayaasha gamma-aminobutyric acid (GABA) si ay uga caawiso dheelitirka jawiga neerfayaasha. Iyada oo si togan u saamaysa neerfayaasha kiciya iyo kuwa joojiya, nefiracetam waxay ka caawisaa ilaalinta shaqada maskaxda ee ugu fiican, sidaas darteedna waxay hagaajinaysaa diiradda, feejignaanta, iyo waxqabadka garashada guud.
Muuqaalka
(1) Nadiifnimo sare: Nefiracetam waxay heli kartaa badeecooyin saafi ah iyada oo loo marayo hababka wax soo saarka ee sifaynta. Nadiifnimo sare waxay ka dhigan tahay helitaan wanaagsan oo noolaha ah iyo falcelin xun oo yar.
(2) Badbaadada: Badbaado sare, falcelin xun oo yar.
(3) Xasillooni: Nefiracetam waxay leedahay xasillooni wanaagsan waxayna ilaalin kartaa firfircoonideeda iyo saameynteeda iyadoo la raacayo jawiyo iyo xaalado kaydin oo kala duwan.
Codsiyada
Nefiracetam waa nooc ka mid ah hydrophobic derivative oo ka soo jeeda piracetam, kaas oo guud ahaan loo arko inuu yahay walax mas'uul ka ah helitaanka kanaalada calcium ee jirka iyo wareejinta aan tooska ahayn ee walxaha calaamadaynta kicinta sida qayb ka mid ah agonist-ka kanaalada calcium ion. Goobta isku xidhka Glycine ee NDMA receptor. Iyada oo loo marayo saamaynta ay ku leedahay cortex-ka maskaxda, nefiracetam waxay kor u qaadi kartaa awoodaha garashada waxayna ka hortagi kartaa khalkhalka waxbarashada iyo xusuusta. Ma laha sifooyin agonist-ka receptor-ka muscarinic ama antagonist, mana joojiso dhaqdhaqaaqa acetylcholinease. Sidaa darteed, saameynteeda ka hortagga amnestic iyo xoojinta xusuusta waxaa lagu gaaraa iyadoo la hagaajinayo sii deynta acetylcholine ee cortex-ka maskaxda.
