7,8-Dihydroxyflavone (7,8-DHF) soo saaraha budada CAS No.: 38183-03-8 98.0% nadiifinta min.maaddooyinka dheeriga ah
Qiyaasta Alaabta
| Magaca alaabta | 7,8-Dihydroxyflavone |
| Magac kale | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-kow |
| CAS Maya. | 38183-03-8 |
| qaacidada molecular | C15H10O4 |
| Miisaanka molecular | 254.24 |
| daahirnimo | 98.0% |
| Muuqashada | Budada jaalaha ah |
| Codsiga | Kaabista Cunnada Qalabka Ceyriinka ah |
hordhaca alaabta
7,8-Dihydroxyflavone, sidoo kale loo yaqaan 7,8-DHF, waa flavonoid si dabiici ah u dhaca oo laga helo dhir kala duwan, oo ay ku jiraan Tridacna tridacna.Waxaa loo yaqaanaa sifooyinka antioxidant iyo neurotrophic, mid ka mid ah dhinacyada ugu xiisaha badan ee 7,8-dihydroxyflavone waa awooddeeda si ay u taageerto caafimaadka maskaxda iyo kor u qaadida shaqada garashada.Cilmi-baaristu waxay muujinaysaa in xaruntani ay u shaqeyso sidii neurotrophin awood leh, oo kicinaysa koritaanka iyo badbaadada neerfayaasha maskaxda.Daraasadaha lagu sameeyay xayawaanka shaybaarka ayaa muujiyay in 7,8-DHF ay si weyn u wanaajiso xusuusta iyo kartida waxbarashada.Iyadoo kor loo qaadayo samaynta isku xirka synaptik ee cusub iyo kor u qaadista xidhiidhka ka dhexeeya unugyada maskaxda, xaruntani waxay ballan qaadaysaa inay furto awooddeena garashada.Intaa waxaa dheer, 7,8-dihydroxyflavone waxay la falgashaa xajiyayaasha serotonin ee maskaxda, kuwaas oo ku lug leh xakamaynta niyadda.Marka la beddelo reseptors kuwaas, waxa laga yaabaa in ay awoodaan in ay yareeyaan calaamadaha walaaca iyo niyad-jabka.
Muuqaal
(1) Nadiifin sare: 7,8-Dihydroxyflavone waxay ku heli kartaa alaab saafi ah iyada oo loo marayo soo saarista dabiiciga ah iyo habka wax soo saarka wanaagsan.Nadaafadda sare waxay ka dhigan tahay helitaan noole oo wanaagsan iyo falcelin xun oo yar.
(2) Badbaadada: 7,8-Dihydroxyflavone waa badeeco dabiici ah oo la xaqiijiyay inay badbaado u tahay bini'aadamka.Inta lagu jiro qiyaasta qiyaasta, ma laha wax sun ah ama waxyeellooyin.
(3) Xasilloonida: 7,8-Dihydroxyflavone waxay leedahay xasillooni wanaagsan waxayna sii wadi kartaa dhaqdhaqaaqeeda iyo saameynteeda xaaladaha deegaanka iyo kaydinta kala duwan.
(4) Si fudud ayaa loo nuugi karaa: 7,8-Dihydroxyflavone si dhakhso ah ayuu u nuugi karaa jidhka bini'aadamka, wuxuu geli karaa wareegga dhiigga iyada oo loo marayo marinka mindhicirka, wuxuuna u qaybin karaa unugyo iyo xubno kala duwan.
Codsiyada
7, 8-DHF, oo ah firfircoone yar yar oo wax ku ool ah oo ka mid ah soo-dhoweynta TrkB, wuxuu ciyaari karaa doorka ilaalinta neerfaha, dib-u-soo-nooleynta neuron, nidaaminta balaastikada synaptik, iwm. hagaajinta calaamadaha barashada shucuureed iyo hoos u dhaca xusuusta goobta, hoos u dhaca awooda garashada, hoos u dhaca dhaqdhaqaaqa dhaqdhaqaaqa iyo calaamadaha kale ee cudurada habdhiska dareenka sida cudurka Alzheimers ama moodooyinka xayawaanka gabowga, Iyo yaraynta phenotypes la xidhiidha cudurka dhimirka iyo xayawaanka buuran.Dhanka kale, ilaa hadda, wax saameyn ah oo sun ah oo 7,8-DHF ah lagama helin xayawaanka tijaabada ah.7,8-DHF waxay leedahay karti iyo qiimo weyn oo ka hortagga iyo daaweynta arrimaha BDNF/TrkB.
