Soo saaraha budada 7,8-Dihydroxyflavone (7,8-DHF) Lambarka CAS: 38183-03-8 98.0% daahirnimo ugu yaraan maaddooyinka dheeraadka ah
Fiidiyowga Badeecada
Cabbiraadaha Badeecada
| Magaca alaabta | 7,8-Dihydroxyflavone |
| Magac kale | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8-(RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-mid |
| Lambarka CAS. | 38183-03-8 |
| Qaacidada moolikaalka | C15H10O4 |
| Miisaanka molecular-ka | 254.24 |
| Daahirnimo | 98.0% |
| Muuqaalka | Budada jaalaha ah |
| Codsiga | Qalabka Cuntada ee Cayriin ah |
Soo bandhigida badeecada
7,8-Dihydroxyflavone, oo sidoo kale loo yaqaan 7,8-DHF, waa flavonoid dabiici ah oo laga helo dhir kala duwan, oo ay ku jiraan Tridacna tridacna. Loo yaqaan sifooyinkeeda antioxidant-ka iyo neurotrophic, mid ka mid ah dhinacyada ugu xiisaha badan ee 7,8-dihydroxyflavone waa awooddeeda ay ku taageerto caafimaadka maskaxda iyo kor u qaadida shaqada garashada. Cilmi-baaristu waxay muujinaysaa in isku-dhafkan uu u dhaqmo sidii neurotrophin xooggan, isagoo kicinaya koritaanka iyo badbaadada neerfayaasha maskaxda. Daraasadaha xayawaanka shaybaarka ayaa muujiyay in 7,8-DHF uu si weyn u hagaajiyo awoodaha xusuusta iyo barashada. Iyada oo kor u qaadaysa sameynta xiriiro cusub oo synaptic ah iyo kor u qaadista isgaarsiinta u dhaxaysa unugyada maskaxda, isku-dhafkan wuxuu ballan qaadayaa inuu furo awooddeenna garashada. Intaa waxaa dheer, 7,8-dihydroxyflavone wuxuu la falgalaa soo-dhoweeyayaasha serotonin-ka maskaxda, kuwaas oo ku lug leh nidaaminta niyadda. Iyada oo la habaynayo soo-dhoweeyayaashan, waxay awood u yeelan kartaa inay yareyso calaamadaha walwalka iyo niyad-jabka.
Muuqaalka
(1) Nadiifnimo sare: 7,8-Dihydroxyflavone wuxuu heli karaa badeecooyin saafi ah oo heer sare ah iyada oo loo marayo soo saarista dabiiciga ah iyo habka wax soo saarka wanaagsan. Nadiifnimo sare waxay ka dhigan tahay helitaan wanaagsan oo noolaha ah iyo falcelin xun oo yar.
(2) Badbaadada: 7,8-Dihydroxyflavone waa badeeco dabiici ah oo la xaqiijiyay inay ammaan u tahay aadanaha. Qiyaasta qiyaasta, ma laha sun ama waxyeellooyin.
(3) Xasillooni: 7,8-Dihydroxyflavone waxay leedahay xasillooni wanaagsan waxayna ilaalin kartaa firfircoonideeda iyo saameynteeda xaaladaha deegaanka iyo kaydinta ee kala duwan.
(4) Si fudud loo nuugo: 7,8-Dihydroxyflavone si dhakhso ah ayuu u nuugi karaa jirka bini'aadamka, wuxuuna geli karaa wareegga dhiigga isagoo maraya xiidmaha, wuxuuna ku faafi karaa unugyo iyo xubno kala duwan.
Codsiyada
7, 8-DHF, oo ah firfircooni yar oo wax ku ool ah oo ku saabsan soo-dhoweeyaha TrkB, ayaa ciyaari kara doorka ilaalinta neerfaha, dib-u-cusboonaysiinta neerfaha, nidaaminta balaastikada synaptic, iwm. iyadoo la dayayo isku-xidhka gaarka ah ee BDNF ee TrkB iyo kicinta waddooyinka calaamadaha hoose, si si weyn loogu hagaajiyo calaamadaha barashada shucuurta iyo hoos u dhaca xusuusta booska, hoos u dhaca awoodda garashada, hoos u dhaca shaqada dhaqdhaqaaqa iyo calaamadaha kale ee cudurka habdhiska neerfaha sida cudurka Alzheimer ama moodooyinka xayawaanka ee gaboobay, Iyo yaraynta noocyada la xiriira ee cudurrada dhimirka iyo xayawaanka cayilan. Dhanka kale, ilaa hadda, ma jiraan waxyeellooyin sun ah oo muhiim ah oo 7,8-DHF ah oo laga helay xayawaanka tijaabada ah. 7,8-DHF waxay leedahay awood weyn iyo qiimo ka hortagga iyo daaweynta arrimaha la xiriira BDNF/TrkB.
