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Soo saaraha budada 7P Compound CAS No.: 1890208-58-8 99% nadiifinta min. maaddooyinka dheeriga ah

Sharaxaad Gaaban:

Isku-dhafka 7p ayaa la muujiyay si uu u kiciyo kobaca GAP-43-positive axon ee qaabka xayawaanka ee dhaawaca dareemayaasha indhaha, taas oo soo jeedinaysa in waxqabadka neurite ee ka soo baxa xarunta 7p in vitro uu u tarjumayo kicinta dib u soo kabashada axon ee vivo.


Faahfaahinta Alaabta

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Fiidiyowga Alaabta

Qiyaasta Alaabta

Magaca alaabta

Isku dhafka 7P

Magac kale

Isku dhafka7P;2-[(2-methoxyphenyl) [(4-methylphenyl) sulfonyl] amino] -N- (4-methoxy-3-pyridinyl) acetamide;

2- (N- (2-methoxyphenyl) -4-methylphenylsulfonamido) - (4-methoxypyridin-3-yl) acetamide

CAS Maya.

1890208-58-8

qaacidada molecular

C22H23N3O5S

Miisaanka molecular

441.51

daahirnimo

99.0%

Muuqashada

budo cad

Codsiga

Nootropic

hordhaca alaabta

Isku dhafka 7P waxaa loola jeedaa isku dhis dabiici ah oo gaar ah oo ka kooban todoba atamka kaarboon. Kiimikada dabiiciga ah, kaarboonku waa curiye muhiim ah sababtoo ah waxay samayn kartaa curaarta xasilloon ee atamka kale, oo ay ku jiraan atamka kaarboonka, si ay u sameeyaan unugyo isku dhafan. Unugyadani waxay yeelan karaan hanti iyo shaqooyin kala duwan, iyagoo ka dhigaya isku-dhisyada kaarboon-ku-salaysan ee dhismaha nolosha. Noocyada xayawaanka ee dhaawaca dareemaha indhaha, xarunta 7p ayaa lagu muujiyay in ay kiciso kobaca GAP-43-positive axon, taas oo soo jeedinaysa in dhaqdhaqaaqa koritaanka neurite ee xarunta 7p in vitro ay u tarjumayso kicinta dib u soo kabashada axonal ee vivo. Isku-dhafka 7P budada waa caddaan ama budo cad-cad oo loo soo saaray sidii isku-darka tandem si loo aqoonsado laba-qabta tromboxane antagonist antagonist. Dhab ahaantii, xarunta 7p waxay muujisay xulashada prostaglandin I2 synthase (PTGIS, CYP8A1) marka loo eego thromboxane synthase (CYP5A1). Xarunta nootropic 7P budada waxay kor u qaadaa korriinka Gap-43-positive axon, taas oo kicinaysa dib u soo kabashada axonal ee jirka. Complex 7p oo tayo sare leh waxaa loogu talagalay in lagu wanaajiyo isuduwidda, wanaajiso niyadda iyo caawinta la dagaalanka daalka. Waxa kale oo ay ka hortagtaa oksaydheynta maskaxda waxayna ka caawisaa la dagaalanka dhaawaca maskaxda ee ay keento cabbitaanka khamriga.

Muuqaal

结构图

(1) Nadiifin sare: Isku dhafka 7P wuxuu ku heli karaa badeecooyin nadiif ah oo sarreeya iyada oo loo marayo hababka wax soo saarka ee la safeeyey. Nadaafadda sare waxay ka dhigan tahay helitaan noole oo wanaagsan iyo falcelin xun oo yar.

(2) Badbaadada: Compound 7P ayaa la xaqiijiyay inuu badbaado u yahay jidhka bini'aadamka.

(3) Xasilooni: Compound 7P waxay leedahay xasillooni wanaagsan waxayna sii wadi kartaa dhaqdhaqaaqeeda iyo saameynteeda hoos yimaada deegaan iyo xaalado kaydin oo kala duwan.

Codsiyada

Compound 7p waxa ay wanaajisaa soo bixitaanka neurite neurons-yada aasaasiga ah ee ka soo jeeda hippocampus, kiliyaha maskaxda, iyo retina waxayna keentaa dib u soo kabashada dareemayaasha indhaha ee moodooyinka xayawaanka ee dhaawaca dareemayaasha indhaha. Waxa kale oo ay xoojisaa isku-duwidda, dawaysaa dhaawaca maskaxda ee la xidhiidha khamriga, waxaanay ka hortagtaa oxidation agagaarka maskaxda. Waxa kale oo ay ka caawisaa hagaajinta niyadda iyo la dagaalanka daalka.


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