Soo saaraha budada Galantamine Hydrobromide Lambarka CAS: 1953-04-4 98% daahirnimo ugu yaraan maaddooyinka dheeraadka ah
Cabbiraadaha Badeecada
| Magaca alaabta | Galantamine Hydrobromide |
| Magac kale | Galanthamine hydrobromide; Galantamine HBr; Galanthamine HBr; (4aS,6R,8aS) -4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,2-ef] [2]benzazepin-6-ol, Hydrobromide |
| Lambarka CAS. | 1953-04-4 |
| Qaacidada moolikaalka | C17H21NO3.HBr |
| Miisaanka molecular-ka | 368.27 |
| Daahirnimo | 98.0% |
| Muuqaalka | budada cad ilaa budada cad |
| Baakad | 1kg/bac 10kgs, 25kgs/durbaan |
| Codsiga | nootropics |
Soo bandhigida badeecada
Galantamine hydrobromide waa benzazepine laga soo qaatay nalalka iyo ubaxyada narcissus, osmanthus, ama canna. Sidoo kale waa daawo afka laga qaato oo ka hortagta cholinesterase. Iyada oo ah ligand loogu talagalay soo-dhoweeyayaasha nicotinic acetylcholine, waxaa si weyn loogu isticmaalay in lagu xoojiyo shaqada neerfaha. Shaqadeedu waa inay si tartan ah oo dib-u-noqosho leh u joojiso acetylcholinesterase, taasoo kordhinaysa diiradda acetylcholine. Marka la nuugo dhiigga, galantamine hydrobromide si fudud ayaa loogu nuugo qaybo kala duwan oo jirka ah, oo ay ku jiraan maskaxda. Waxay ku xidhaa soo-dhoweeyayaasha nicotinic acetylcholine, taasoo keenta isbeddello qaab-dhismeed iyo kordhinta sii-deynta acetylcholine. Waxay sidoo kale ka shaqeysaa iyadoo la tartamaysa oo dib u celinaysa saamaynta ka hortagga cholinesterase. Iyada oo la joojinayo cholinesterase, waxay ka hortagtaa burburka acetylcholine, taasoo kordhinaysa heerarka iyo muddada neerfahan awoodda badan. Galantamine waxay sidoo kale hagaajin kartaa waxbarashada iyo xusuusta, ka hortagtaa bararka maskaxda, waxayna ilaalin kartaa heerarka sare ee neerfayaasha iyadoo la ilaalinayo sharafta neerfayaasha iyo synapses.
Muuqaalka
(1) Nadiifnimo sare: Galantamine hydrobromide waxay noqon kartaa badeeco saafi ah oo heer sare ah iyada oo loo marayo hababka wax soo saarka ee sifaynta. Nadiifnimo sare waxay ka dhigan tahay helitaan wanaagsan oo noolaha ah iyo falcelin xun oo yar.
(2) Badbaadada: Galantamine hydrobromide waxaa la xaqiijiyay inay ammaan u tahay jirka aadanaha.
(3) Xasillooni: Galantamine hydrobromide waxay leedahay xasillooni wanaagsan waxayna ilaalin kartaa dhaqdhaqaaqeeda iyo saameynteeda iyadoo la raacayo jawiyo iyo xaalado kaydin oo kala duwan.
Codsiyada
Kaabis cunto ahaan, galantamine hydrobromide waxay hagaajin kartaa xusuusta, miyir-qabka, iyo awoodda ay u leedahay inay qabato hawlo maalmeedka. Waxay u shaqeysaa iyadoo dib u soo celinaysa dheelitirka walxaha dabiiciga ah qaarkood (neurotransmitters) ee maskaxda, taas oo kordhisa xawaaraha sameynta xusuusta waxayna hagaajisaa haynta faahfaahinta iyo xaqiiqooyinka. Intaa waxaa dheer, galantamine hydrobromide si toos ah ama si dadban ayuu u saameeyaa neuroplasticity. Waxay kicisaa balaastikada synaptic iyadoo kicinaysa microglia iyo astrocytes. Galantamine waxay bixisaa ilaalin antioxidant ah oo ka dhan ah walbahaarka oksaydhka ee ay keento xagjirrada xorta ah.
